HMG 75 IU – 10 Vials

HMG (Human Menopausal Gonadotropin, also known as menotropin) is a purified glycoprotein hormone research compound extracted from the urine of postmenopausal women, consisting of a near 1:1 ratio of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) bioactivity (typically 75 IU each per vial), with minor amounts of human chorionic gonadotropin (hCG) contributing to LH-like activity. It functions as a dual gonadotropin agonist that binds to FSH and LH receptors on gonadal cells. In preclinical and clinical models, FSH components stimulate follicular development and maturation in females by promoting granulosa cell proliferation, aromatase expression, and estradiol production, while LH components enhance theca cell androgen synthesis, support final follicular maturation, and trigger ovulation or spermatogenesis in males via Leydig cell testosterone production and Sertoli cell support for sperm maturation. In research settings, HMG is utilized to investigate mechanisms of gonadal stimulation, ovulation induction protocols, spermatogenesis restoration (e.g., in hypogonadotropic hypogonadism or post-anabolic steroid suppression models), assisted reproductive technologies (e.g., IVF/ICSI cycle optimization), endocrine feedback loops in the hypothalamic-pituitary-gonadal axis, and therapeutic strategies for infertility, polycystic ovary syndrome (PCOS), and hormone-dependent reproductive disorders, often in combination with agents like hCG, GnRH analogs, or aromatase inhibitors to modulate follicular recruitment, oocyte quality, and testicular function